SFI Health

Brahmi (Bacopa monnieri CDRI 08)

Memory and concentration support

Bacopa monnieri is used to support memory and learning retention. An exclusive extract of the Bacopa plant is the key ingredient of KeenMind.

Bacopa monnieri, commonly known as Brahmi or Bacopa used in Keenmind, is a medicinal herb, used for generations in Ayurvedic medicine for supporting memory, concentration and learning capacity.

In KeenMind®, a specific standardised extract of Bacopa monnieri, known as CDRI 08, is used. KeenMind with CDRI 08 has been extensively researched for over 40 years* to support cognitive health.1-8

Discover more about CDRI 08 used in KeenMind and the key studies that support its benefits.

Always read the label. Follow the directions of use. Packaging and product claims may vary depending on country-specific regulations. Products available in selected markets only

Bacopa monnieri in history

Bacopa monnieri, also known as Brahmi, is a small creeping herb found throughout the Indian subcontinent.

It has been used in Ayurvedic medicine for almost 3000 years.Throughout this time, it has been associated with a variety of health benefits including heightened learning capacity, promoting memory and concentration, as a nerve tonic and to support cardiovascular health. 7 

It is the memory and learning effects of Bacopa that have attracted the most attention in the last few decades and, in doing so, have become the subject of much clinical research.

Bacopa monnieri in history

The specific extract used in KeenMind: CDRI 08

CDRI 08 is the specific Bacopa monnieri extract used by SFI Health in KeenMind. It was first researched in the 1970s by the Indian government’s Central Drug Research Institute, and has been the subject of research for more than 40 years* to support its benefits for cognitive health.

The memory supporting effect of CDRI 08 is based on numerous clinical trials. Results from these clinical trials suggest that CDRI 08 in KeenMind helps to:1-6

  • Maintain healthy cognitive function
  • Improve working memory
  • Assist in learning retention
  • Assist with concentration and focus as well as keeping to task and maintaining attention span
  • Can be beneficial during times of stress or mild anxiety
The specific extract used in KeenMind: CDRI 08

Research on how CDRI 08 works

Pre-clinical studies suggest that Bacopa monnieri in CDRI 08 can help support brain function in several different ways.

Antioxidant effects to help support against oxidative stress 8,9

Neuroprotective effects involved in supporting healthy brain function8,9

Regulation of communication between brain cells and activity associated with learning and memory10

Affecting neurotransmitter systems like serotonin, dopamine and acetylcholine that  involved with memory-related processes11,12

Adaptogenic effects that can help support the body in times of physical and mental stress13

Research on how CDRI 08 works

CDRI 08 in KeenMind: Clinical trials


The specific CDRI 08 extract of Bacopa monnieri has been researched in multiple randomised controlled trials demonstrating that it can help improve cognitive function and is well tolerated at the recommended dose.1-6 The table below covers a selection of key clinical studies on CDRI 08.

Stough 2001

46 healthy adults studied over 12 weeks

Significant improvement

vs. placebo for:

  • speed of visual information processing learning rate memory consolidation forgetting rate mild state of anxiety

Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.

Roodenrys 2002

76 healthy adults studied over 3 months

Significant improvement

vs. placebo for:

  • retention of new information

Roodenrys S, et al. Neuropsychopharmacology 2002;27(2):279-281.

Stough 2008

107 healthy adults studied over 90 days

Significant improvement

vs. placebo for:

  • working memory mistakes in visual information processing

Stough C, et al. Phytother Res 2008;22(12):1629-634.

Raghav 2006

40 adults with memory concerns studied over 12 weeks

Significant improvement

vs. placebo for:

  • mental control logical memory paired associated learning

Raghav S, et al. Indian J Psychiatry 2006;48(4):238-242.

Benson 2014

17 healthy adults studied over 2 hours

Positive Effect

vs. placebo for:

  • acute cognitive function mood stress

Benson S, et al. Phytother Res 2014;28(4):551-559.

Downey 2012

24 healthy adults studied over 2 hours

Positive Effect

vs. placebo for:

  • improved cognitive performance, including: information processing, decision making time, and attention or freedom from distractibility

Downey LA, et al. Phytother Res 2012;27(9):1407-1413.

SFI Health Difference

Natural healthcare products can vary considerably depending on how they are produced. Keenmind is produced according to our 'Source to Patient' philosophy which aims to deliver a high quality and consistent extract, from batch to batch so that you can be confident that it can deliver the health benefits demonstrated in the clinical research.

This helps ensure that the natural healthcare products you are getting contains the exact ingredient, in the exact same amounts demonstrated in the clinical research. That's the SFI Health difference.

CDRI 08: A Summary

Consistent quality

Through our rigorous processes, quality controls and extensive testing we help ensure that every batch of KeenMind can provide the desired health outcomes demonstrated by clinical studies.

40 years of research

Beginning in 1974* by the Central Drug Research Institute (CDRI) in India and more recently in Australia.

8 Clinical trials

KeenMind clinical studies support its role in improving cognitive function1-8

Recommended worldwide

to support cognitive health, memory, concentration and learning retention.

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  1. Stough C, et al. Psychopharmacology (Berl) 2001;156(4):481-484.
  2. Roodenrys S, et al. Neuropsychopharmacology 2002;27(2):279-281.
  3. Stough C, et al. Phytother Res 2008;22(12):1629-634.
  4. Raghav S, et al. Indian J Psychiatry 2006;48(4):238-242.
  5. Benson S, et al. Phytother Res 2014;28(4):551-559.
  6. Downey LA, et al. Phytother Res 2012;27(9):1407-1413.
  7. Negi KS, et al. Indian J Psychiatry 2000;42(2):supplement.
  8. Sharma DMD [thesis]. BRD Medical College DDU University, Uttar Pradesh, India, 2000.
  9. Singh HK. Nutrients 2013;5(2):478-497.
  10. Simpson et al. 2015. Evid Based Complement Alternat Med 2014; Article ID 615384.
  11. Bhattacharya SK et al Phytother. Res. 2000;14: 174–179
  12. Mondal P et al. Evid Based Complementary Altern Med 2015; Article ID 535013.
  13. Das et al. Pharmacol Biochem Behav 2002; 73 (4):893-900
  14. Rajan et al. Neurochem Res 2011; 36 (11):2136-44 [S14-0165].
  15. Rai D, et al. Pharmacol Biochem Behav 2003;75:823-830.

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